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SUMMARY
When a Windows XP-based computer is running low on disk space, you receive a “Low Disk Space” message that, when clicked, starts the Disk Cleanup Wizard. This article describes the conditions in which you receive the “Low Disk Space” message.
MORE INFORMATION
WARNING: If you use Registry Editor incorrectly, you may cause serious problems that may require you to reinstall your operating system. Microsoft cannot guarantee that you can solve problems that result from using Registry Editor incorrectly. Use Registry Editor at your own risk. When free disk space reaches 200 megabytes (MB), you receive the following message for 10 seconds, once per session:
You are running out of disk space on [drive]. To free space on this drive by deleting old or unnecessary files, click here.
When free disk space reaches 80 MB, you receive the following message for 30 seconds, every four hours, twice per session:
You are running very low on disk space on [drive]. To free space on this drive by deleting old or unnecessary files, click here.
When free disk reaches 50 MB, you receive the following message for 30 seconds, every five minutes, until free space is above 50 MB:
You are running very low on disk space on [drive]. To free space on this drive by deleting old or unnecessary files, click here.
Note There is a registry value you can set to disable this feature. To disable low disk space checks, follow these steps, log off, and then log on again: Follow these steps, and then quit Registry Editor: 1. Click Start, click Run, type regedit, and then click OK.
2. Locate and then click the following key in the registry:
HKEY_CURRENT_USER\SOFTWARE\Microsoft\Windows\CurrentVersion\Policies\Explorer
3. On the Edit menu, point to New, and then click DWORD Value.
4. Type NoLowDiskSpaceChecks, and then press ENTER.
5. On the Edit menu, click Modify.
6. Type 1, and then click OK.

http://support.microsoft.com/kb/285107